
Ph.D Engineering · On-going
Physiological and Pathophysiological Characterization of Bladder Outflow
Urogenital conditions such as urinary stones and renal insufficiency account for a high rate of emergency admissions and a significant risk of recurrenceThe work characterises bladder outflow under a range of boundary conditions on an in vitro flow simulator, then trains a data-driven flow transformation able to generalise those measurements to complex, patient-specific bladder geometries.
Those models are assembled into a digital twin of an affected bladder, validated against ultrasound and PIV data. Urinary stones serve as the proof of concept for a non-invasive diagnostic tool aimed at both clinical practice and medical device design.